Cytopathology usually used to aid in the diagnosis of cancer, but also helps in the diagnosis of certain infectious diseases and other inflammatory conditions. Cancer Cytopathology is generally used on samples of free cells or tissue fragments, in contrast to histopathology, which studies whole tissues. Cytopathologic tests are sometimes called smear tests because the samples may be smeared across a glass microscope slide for subsequent staining and microscopic examination. Gallbladder cancer is a relatively uncommon cancer and can be cure by fine needle aspiration material. However, cytology samples may be prepared in other ways, including cytocentrifugation. Different types of smear tests may also be used for cancer diagnosis. In this sense, it is termed a cytological smear. Epidemiology of Breast Cancer is the most commonly diagnosed cancer among women, with approximately 182,000 women diagnosed with breast cancer annually in the United States, accounting for approximately 26% of all incident cancers among women. Each year, 40,000 women die of breast cancer, making it the second-leading cause of cancer deaths among American women after lung cancer. The lifetime risk of dying of breast cancer is approximately 3.4%.